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Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Aug 2020
Randomized Controlled TrialOptimum Blood Pressure in Patients With Shock After Acute Myocardial Infarction and Cardiac Arrest.
In patients with shock after acute myocardial infarction (AMI), the optimal level of pharmacologic support is unknown. Whereas higher doses may increase myocardial oxygen consumption and induce arrhythmias, diastolic hypotension may reduce coronary perfusion and increase infarct size. ⋯ In post-cardiac arrest patients with shock after AMI, targeting MAP between 80/85 and 100 mm Hg with additional use of inotropes and vasopressors was associated with smaller myocardial injury.