Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Aug 2010
Survival in schistosomiasis-associated pulmonary arterial hypertension.
The objective of this study was to evaluate the natural history of untreated schistosomiasis-associated pulmonary arterial hypertension (Sch-PAH) patients as compared to idiopathic pulmonary arterial hypertension (IPAH) with respect to hemodynamics recorded at presentation and 36 months survival. ⋯ Sch-PAH has a more benign clinical course than IPAH despite a lack of demonstrable acute vasoreactivity at hemodynamic evaluation.
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J. Am. Coll. Cardiol. · Aug 2010
Earlier intervention in the management of hypercholesterolemia: what are we waiting for?
The thesis advanced here is that we are initiating treatment of hypercholesterolemia (and other risk factors) too late in life. Initiating treatment at, for example, age 30 years instead of age 60 years might very well prevent not just 30% of events, as in the 5-year statin trials, but perhaps as many as 60%.