Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Oct 2018
Emergency Department Visits by Children With Congenital Heart Disease.
Data related to the epidemiology and resource utilization of congenital heart disease (CHD)-related emergency department (ED) visits in the pediatric population is limited. ⋯ Children with CHD presenting to the ED represent a medically complex population at increased risk for morbidity, mortality, and resource utilization compared with those without CHD. Over 9 years, charges increased, but the mortality rate improved.
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J. Am. Coll. Cardiol. · Oct 2018
Randomized Controlled Trial Multicenter StudyLosartan Versus Atenolol for Prevention of Aortic Dilation in Patients With Marfan Syndrome.
Beta-blockers are the standard treatment in Marfan syndrome (MFS). Recent clinical trials with limited follow-up yielded conflicting results on losartan's effectiveness in MFS. ⋯ Long-term outcome of Marfan syndrome patients randomly assigned to losartan or atenolol showed no differences in aortic dilation rate or presence of clinical events between treatment groups. Therefore, losartan might be a useful, low-risk alternative to beta-blockers in the long-term management of these patients.