Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · May 2005
Relationship between B-type natriuretic peptides and pulmonary capillary wedge pressure in the intensive care unit.
We examined whether B-type natriuretic peptides (BNP) can serve as noninvasive markers of pulmonary capillary wedge pressure (PCWP) in the setting of critical illness. ⋯ The BNPs are markedly elevated, yet show only weak correlations to PCWP in ICU patients requiring invasive hemodynamic monitoring. Thus, a single value for BNP or NT-proBNP may not be a clinically useful noninvasive marker of filling pressures in the critically ill patient. This appears to be especially true in patients with impaired renal function.
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J. Am. Coll. Cardiol. · Apr 2005
Comparative StudyCommunity screening for left ventricular systolic dysfunction using plasma and urinary natriuretic peptides.
We sought to compare urinary and plasma N-terminal pro-brain natriuretic peptide (N-BNP) in left ventricular systolic dysfunction (LVSD) diagnosis. ⋯ Urinary N-BNP used together with plasma N-BNP could reduce the echocardiographic burden in screening programs.
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J. Am. Coll. Cardiol. · Apr 2005
Comparative StudyTreatment of saphenous vein graft lesions with drug-eluting stents: immediate and midterm outcome.
The purpose of the present report was to evaluate clinical and angiographic outcomes of drug-eluting stent (DES) implantation in saphenous vein graft (SVG) lesions. ⋯ Compared to BMS implantation, DES implantation in SVG lesions appears safe with favorable and improved mid-term outcomes.
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J. Am. Coll. Cardiol. · Apr 2005
Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery disease.
This study was designed to explore contributions of plasma total triglycerides (TGs) and type III hyperlipidemia to the risk of premature familial coronary artery disease (CAD). ⋯ The association between the plasma TG level and premature familial CAD is strong, graded, and independent. Risk of CAD is also strikingly elevated with type III hyperlipidemia.