Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Nov 2015
Early and Late Outcomes of Surgical Treatment in Carcinoid Heart Disease.
Symptoms and survival of patients with carcinoid syndrome have improved, but development of carcinoid heart disease (CaHD) continues to decrease survival. ⋯ Operative mortality associated with valve replacement surgery for CaHD has decreased. Symptomatic and survival benefit is noted in most patients when CaHD is managed by an experienced multidisciplinary team.
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J. Am. Coll. Cardiol. · Nov 2015
Randomized Controlled Trial Multicenter StudyComparing LCZ696 with enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores: an analysis of mortality and morbidity in PARADIGM-HF.
Although most patients in the PARADIGM-HF (Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) trial had mild symptoms, there is a poor correlation between reported functional limitation and prognosis in heart failure. ⋯ Although most PARADIGM-HF patients had mild symptoms, many were at high risk for adverse outcomes and obtained a large absolute benefit from LCZ696, compared with enalapril, over a relatively short treatment period. LCZ696's benefit was consistent across the spectrum of risk. (PARADIGM-HF trial [Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure]; NCT01035255).
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J. Am. Coll. Cardiol. · Nov 2015
Temporal Trends and Sex Differences in Revascularization and Outcomes of ST-Segment Elevation Myocardial Infarction in Younger Adults in the United States.
Older women presenting with ST-segment elevation myocardial infarction (STEMI) are less likely to receive revascularization and have worse outcomes relative to their male counterparts. ⋯ Younger women are less likely to receive revascularization for STEMI and have higher in-hospital mortality as compared with younger men. Use of percutaneous coronary intervention for STEMI and in-hospital mortality have increased, whereas length of stay has decreased in both sexes over the past several years.
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J. Am. Coll. Cardiol. · Oct 2015
Household Disposable Income and Long-Term Survival After Cardiac Surgery: A Swedish Nationwide Cohort Study in 100,534 Patients.
Lower socioeconomic groups face higher mortality risk, possibly due to a higher burden of cardiovascular risk factors. The independent association between income and survival following cardiac surgery is not known. ⋯ We found a strong inverse association between income and mortality following cardiac surgery in Sweden that was independent of other socioeconomic status variables, comorbidities, and cardiovascular risk profile. Ways to better implement secondary prevention measures should be explored in low-income patient groups. (HeAlth-data Register sTudies of Risk and Outcomes in Cardiac Surgery [HARTROCS]; NCT02276950).