Nutrition research
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Limited evidence suggests that the association between fish consumption and risk of cardiovascular disease may be confounded by some regional-related factors. We aimed to quantify the association of fish consumption with risk of myocardial infarction (MI) and to clarify the shape of the dose-response relation in Western and Asian countries. A systematic literature review was performed in PubMed and Scopus from inception to January 2018. ⋯ A modest U-shaped association was observed in the analysis of Western studies. In conclusion, higher fish consumption was associated with a lower risk of MI. However, considering the observed regional difference in this association, further observational studies are needed to provide more detailed explanations about this difference.