Diagnostic microbiology and infectious disease
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Diagn. Microbiol. Infect. Dis. · Sep 2000
Randomized Controlled Trial Clinical TrialEvaluation of antiseptic-impregnated central venous catheters for prevention of catheter-related infection in intensive care unit patients.
Central venous catheterization represents a significant medical advancement, particularly in the treatment of critical ill. However, there is a high risk of central venous catheters-related infection. A novel antiseptic central venous catheter, made of polyurethane and impregnated with chlorhexidine and silver sulfadiazine, was developed to reduce the risk of catheters-related infection. ⋯ Two of our cases in the control group died directly due to catheter-related candidemia. No adverse reactions such as hypersensitivity or leukopenia were found in the antiseptic catheter group. Our study showed that central venous catheters with antiseptic coating were safe and had less risk of colonization of bacteria and fungi than standard catheters in the critically ill patients.