Journal of hypertension
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Journal of hypertension · Jun 1999
Comparative StudyHyper-responsiveness to angiotensin II is related to cardiac structural adaptation in hypertensive subjects.
Angiotensin II has been found to be a growth stimulating factor for myocardial cells. In humans, angiotensin II infusion causes vasoconstriction in systemic and renal vasculature and leads to aldosterone secretion. Our hypothesis was that hyper-responsiveness to angiotensin II is related to left ventricular mass in human essential hypertension. ⋯ Hyper-responsiveness to angiotensin II is related to an increased left ventricular mass in hypertensive subjects independent of blood pressure.