Journal of hypertension
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Journal of hypertension · Apr 2010
Combined effect of albuminuria and estimated glomerular filtration rate on cardiovascular events and all-cause mortality in uncomplicated hypertensive patients.
Decreased glomerular filtration rate (GFR) and microalbuminuria predict cardiovascular events and mortality in the general population and in high-risk patients. Their combined prognostic power in low-risk patients has never been reported. We assessed the prognostic role of GFR and albuminuria for cardiovascular disease and all-cause mortality in nondiabetic patients with primary hypertension. ⋯ Renal dysfunction is a risk factor for cardiorenal events and all-cause mortality, regardless of traditional confounders, in uncomplicated patients with primary hypertension.