Journal of hypertension
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Journal of hypertension · Aug 2012
Randomized Controlled Trial Comparative StudySequential nephron blockade versus sequential renin-angiotensin system blockade in resistant hypertension: a prospective, randomized, open blinded endpoint study.
To compare two drug regimens to treat resistant hypertension. ⋯ In patients with resistant hypertension, sequential nephron blockade induces a large and well tolerated reduction in blood pressure via a progressive increase in sodium depletion, and is more effective than sequential renin-angiotensin system blockade.
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Journal of hypertension · Aug 2012
Visit-to-visit blood pressure variations: new independent determinants for cognitive function in the elderly at high risk of cardiovascular disease.
Recently, visit-to-visit blood pressure (BP) variability has been shown to be associated with silent cerebral injury and stroke. However, the relationships between visit-to-visit BP variation and cognitive function are not clear. ⋯ In the high-risk elderly, exaggerated visit-to-visit BP fluctuations were significant indicators for cognitive impairment.
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Journal of hypertension · Aug 2012
Vitamin D status partly explains ethnic differences in blood pressure: the 'Surinamese in the Netherlands: study on ethnicity and health'.
To investigate the role of vitamin D in explaining ethnic differences in blood pressure among three ethnic groups in the Netherlands (ethnic Dutch, African Surinamese, and south Asian Surinamese). ⋯ Higher blood pressures and higher hypertension risk in south Asian Surinamese and African Surinamese were partly explained by their poorer vitamin D status. However, even after adjustment, significant ethnic blood pressure differences persisted.