Journal of hypertension
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Journal of hypertension · Jun 2015
2D.06: IN HYPERTENSIVE PATIENTS WITH CHEST PAIN AND NORMAL RESTING ECG THE LOW-COST EXERCISE HIGH-FREQUENCY QRS-ANALYSIS IS COMPARABLE TO THE EXERCISE ECHO.
The novel exercise computer-assisted high-frequency QRS-analysis (ex-HF/QRS) has demonstrated improved sensitivity and specificity over the conventional ST/ECG-segment analysis (ex-ST/ECG) in the detection of myocardial ischemia. The aim of the present study was to compare the diagnostic value of the validated exercise-Echocardiography (ex-Echo), needing skilled cardiologist, with the novel low-cost ex-HF/QRS, including the conventional ST-segment analysis. ⋯ In "intermediate-risk" CP patients, the novel ex-HF/QRS was a valuable diagnostic tool in the crowed Emergency Departments. The test might be proposed to avoid additional costly imaging also because it did not require specialized personnel. However, additional study are needed before it can be recommended as a replacement for current techniques.
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Journal of hypertension · Jun 2015
5A.01: CORONARY ATHEROSCLEROSIS AND ADVERSE OUTCOME IN HYPERTENSIVE PATIENTS WITH RECENT-ONSET ATRIAL FIBRILLATION AND TROPONIN RISE.
Atrial fibrillation (AF), the most common cardiac-arrhythmia in critical-care, has reached a high prevalence in hypertensive patients. Prevention of systemic-embolism is mandatory; unfortunately, evidence to support the treatment of comorbidities as coronary artery disease (CAD) that contribute to excess mortality is lacking, and the mechanism underlying the troponin-rise during AF without acute coronary syndrome (ACS) is unclear. This study investigates the relationship between CAD, stroke and outcomes in patients with troponin-rise and AF. ⋯ Patients with a recent-onset AF and troponin-rise showed a high prevalence of CVE but not stroke, thus CAD might have a role in poor outcomes.
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Journal of hypertension · Jun 2015
Principles of cerebral hemodynamics when intracranial pressure is raised: lessons from the peripheral circulation.
The brain is highly vascular and richly perfused, and dependent on continuous flow for normal function. Although confined within the skull, pressure within the brain is usually less than 15 mmHg, and shows small pulsations related to arterial pulse under normal circumstances. Pulsatile arterial hemodynamics in the brain have been studied before, but are still inadequately understood, especially during changes of intracranial pressure (ICP) after head injury. ⋯ The findings emphasize importance of reducing ICP, when raised, and on the additional benefits of reducing wave reflection from the lower body.
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Journal of hypertension · Jun 2015
4A.10: PREFERENTIAL REDUCTION IN MORNING/NOCTURNAL HYPERTENSION BY RENAL DENERVATION FOR DRUG- RESISTANT HYPERTENSION: A NEW ABPM ANALYSIS OF SYMPLICITY HTN-3 AND HTN-JAPAN.
To study the impact of catheter-based renal artery denervation (RDN) on change in morning and night systolic BP (SBP) defined by ambulatory BP measurements (ABPM) 6 months post-randomization. ⋯ This analysis demonstrated that RDN significantly reduced morning and nighttime SBP compared with control patients suggesting potential benefit of this device approach on cardiovascular protection in drug-resistant hypertension when measurements are captured during higher risk time periods.
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Journal of hypertension · Jun 2015
1C.01: SOLUBLE UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR AS A PROGNOSTIC MARKER OF ALL-CAUSE AND CARDIOVASCULAR MORTALITY IN A BLACK POPULATION.
Elevated inflammatory markers such as C-reactive protein (CRP) and interleukin-6 (IL-6) are well-known risk factors for cardiovascular mortality. The less familiar marker, soluble urokinase plasminogen activator receptor (suPAR), is known to predict cancer, infections and all-cause mortality. We determined whether suPAR, CRP and IL-6 are predictive of both all-cause and cardiovascular mortality in a black population, highly burdened by cardiovascular disease and HIV infection. ⋯ : SuPAR predicted both all-cause and cardiovascular mortality, independent of traditional risk factors, HIV and other inflammatory markers, underlining the prognostic value of suPAR in a black population.