Cancer investigation
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Cancer investigation · Aug 2006
The association between polymorphisms in glutathione S-transferase (GSTM1 and GSTT1) and lung cancer outcome.
Polymorphisms in the glutathione S-transferase (GST) family may be associated with increased risk of lung cancer, somatic changes in lung tumour tissue, and survival. We evaluated survival according to GST polymorphism in lung cancer patients. ⋯ Our preliminary results showed that GSTM1-null genotype was associated with shorter survival.