World journal of urology
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World journal of urology · Apr 2008
Does tourniquet application alter the nitrergic responses of rabbit corpus cavernosum penis? A functional study.
To investigate the effects of short and long periods of tourniquet application on corporal nerves, endothelium and smooth muscle responses. ⋯ The results suggest that long period of tourniquet application altered endothelium-dependent muscarinic receptor-mediated relaxation responses. This is the first functional study that examined the effects of tourniquet application on corpus cavernosum tissue. In conclusion, it can be suggested that if tourniquet is necessary in penile surgery the application time of up to 20 min is more appropriate instead of prolonged usage.