World journal of urology
-
World journal of urology · Aug 2011
Effect of parathyroid hormone on hypogonadism induced bone loss of proximal femur of orchiectomized rat.
Management of hypogonadism-induced osteoporosis in elderly men is still a challenge. We investigated the short-term effects of parathyroid hormone (PTH) treatments on strength, micro-architecture, and mineral density of trochanteric region of orchiectomized rat femur. ⋯ Our finding supports the hypothesis that PTH therapy seems to be a rational therapy in patients with hypogonadism induced bone loss and improves the bone strength of trochanteric region of rat femur.