Journal of neuro-oncology
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Journal of neuro-oncology · Jan 2008
ReviewNew prospects for management and treatment of inoperable and recurrent skull base meningiomas.
Skull base, including optic nerve, cavernous sinus, clival and foramen magnum tumors represent a major challenge for neurosurgeons and neuro-oncologists. Growth regulatory signaling pathways for these tumors are of increasing interest as potential targets for new chemotherapy. ⋯ This article reviews some recent findings pathways that appear to regulate meningioma growth. Potential targets for novel therapies are also discussed.
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Journal of neuro-oncology · Jan 2008
Comparative StudyGamma knife radiosurgery for brainstem metastases: the UCSF experience.
To assess clinical and imaging outcomes in patients treated with Gamma Knife stereotactic radiosurgery (SRS) for brainstem metastases. ⋯ In this series, SRS using a median dose of 16 Gy provided excellent local control with relatively low morbidity in patients with brainstem metastases less than 1 ml or non-melanoma, non-renal cell histology.