Clinical nutrition : official journal of the European Society of Parenteral and Enteral Nutrition
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Physical functioning declines with advancing age and compounds malnutrition, common in elderly populations. A dual-intervention combining oral nutritional support and exercise may delay these changes. Our aims were to assess whether exercise combined with oral nutritional support (ONS) has greater improvements on physical functioning, quality of life and nutritional status than nutrition intervention alone in nutritionally vulnerable older adults. ⋯ This trial was registered at http://www.crd.york.ac.uk/PROSPERO/ as CRD42015027323.
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The amount of energy required to improve clinical outcomes in critically ill adults is unknown. ⋯ The delivery of near target energy when compared to standard care in adult critically ill patients was not associated with an effect on mortality. Because the quality of the evidence across outcomes was very low there is considerable uncertainty surrounding this estimate. This has implications for clinical utility of the evidence within the included reviews.