The American journal of emergency medicine
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Meta Analysis
Can corticosteroids reduce the mortality of patients with severe sepsis? A systematic review and meta-analysis.
Corticosteroids may reduce 28 day mortality in patients with severe sepsis or septic shock.
pearl -
Meta Analysis
Efficacy and outcomes of lipid resuscitation on organophosphate poisoning patients: A systematic review and meta-analysis.
Organophosphate (OP) pesticides are still widely available in developing countries, leading to numerous accidental or suicidal poisonings every year. Lipid emulsion treatments are commonly used in resuscitating OP poisoning patients but few studies regarding their use have been reported. Our meta-analysis aimed to analyze the efficacy and outcomes of lipid resuscitation on OP poisoning patients. ⋯ Based on our meta-analysis of included RCT reports, lipid resuscitation seems likely to help improve prognosis and liver function of OP poisoning patients. However, larger multi-center RCTs are still recommended.