IEEE transactions on medical imaging
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IEEE Trans Med Imaging · Nov 2002
Functional MRI activity characterization using response time shift estimates from curve evolution.
Characterizing the response of the brain to a stimulus based on functional magnetic resonance imaging data is a major challenge due to the fact that the response time delay of the brain may be different from one stimulus phase to the next and from pixel to pixel. To enhance detectability, this work introduces the use of a curve evolution approach that provides separate estimates of the response time shifts at each phase of the stimulus on a pixel-by-pixel basis. ⋯ The algorithm provides a pixel-by-pixel functional characterization of the brain's response. The results based on experimental data show that response time shift estimates, when properly implemented, enhance detectability without sacrificing robustness.