The British journal of oral & maxillofacial surgery
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Br J Oral Maxillofac Surg · Jun 1997
Oral pyogenic granuloma: a review of 38 cases from Ibadan, Nigeria.
Thirty-eight cases of patients with histologically confirmed pyogenic granuloma of the oral cavity were treated at the University College Hospital Dental Centre during the period 1982-1993. The age of the patients at presentation ranged from 5 to 74 years (mean 33) and the male:female ratio was 1:1.2. ⋯ The clinical presentation was generally similar to that in other studies except that most of the lesions were large. All 38 cases were treated by excision and there were no recurrences among those with adequate follow-up.
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Br J Oral Maxillofac Surg · Jun 1997
Randomized Controlled Trial Clinical TrialAre the pharmacokinetics of ibuprofen important determinants for the drug's efficacy in postoperative pain after third molar surgery?
The aim of the present placebo-controlled, crossover study was to evaluate the efficacy and pharmacokinetics of ibuprofen after a single oral dose of soluble ibuprofen 400 mg in 18 patients with postoperative pain after bilateral third molar surgery. Throughout a 5-hour investigation period, patients reported significantly less pain (P < 0.001) after treatment with soluble ibuprofen than after placebo. ⋯ It is concluded that a single dose of soluble ibuprofen 400 mg is an effective analgesic for the control of postoperative pain in the early period after third molar surgery. Efficacy of this preparation does not appear to be directly related to the drug's pharmacokinetic variables in plasma.