Pediatric dermatology
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Pediatric dermatology · Nov 2006
Review Case Reports Comparative StudyChronic disseminated cutaneous blastomycosis in an 11-year old, with a brief review of the literature.
Chronic disseminated cutaneous blastomycosis is rare in children. We discuss an 11-year-old immunocompetent boy who presented with a history of persistent and multiple skin lesions of >1 year's duration. ⋯ Complete resolution of clinical disease occurred after a 6-month course of oral itraconazole. We also present a brief review of the literature focusing on the epidemiology, manifestations, diagnosis, and treatment of pediatric blastomycosis.
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Pediatric dermatology · Nov 2006
Review Case ReportsErythema multiforme due to Mycoplasma pneumoniae infection in two children.
Mycoplasma pneumoniae is an important and highly relevant cause of bullous erythema multiforme, isolated mucositis, and Stevens-Johnson syndrome in children. In this article, we present two children with respiratory Mycoplasma pneumoniae infection and associated cutaneous findings within the spectrum of erythema multiforme. We review the literature associating these three entities with Mycoplasma pneumoniae infection and discuss controversies regarding the classification of erythema multiforme, as well as update reported infectious causes of the bullous form. ⋯ Mycoplasma pneumoniae-associated mucositis and Stevens-Johnson syndrome seem to occur along a spectrum with separate prognosis and potential pathogenesis compared with bullous erythema multiforme. Making the distinction between these conditions is valuable for predicting the child's prognosis. Patients who develop symptoms consistent with these conditions should be appropriately evaluated for Mycoplasma pneumoniae infection and closely monitored.