Vaccine
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Attitudes of general practitioners (GPs) towards A/H1N1 pandemic vaccination are unknown. We conducted a cross-sectional survey with computer-assisted telephone interviewing in the French Regional Panel of General Practices from June 16 to September 22, 2009. Of 1434 respondents representative of GPs in four French regions, 885 (61.7%) were willing to accept A/H1N1 pandemic vaccination for themselves. ⋯ Willingness to accept pandemic vaccination was also significantly associated with being on call for emergencies; positive attitudes towards other protective measures against A/H1N1 influenza virus in the practice; and a higher readiness to provide additional consultations in response to the pandemic. In conclusion, GPs showed a high acceptability of A/H1N1 pandemic vaccination. GPs' involvement in the mass vaccination campaign, which has been neglected by French public health authorities, may have increased uptake rates in the general public.
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Decisions on how to mitigate an evolving pandemic are technically challenging. We present a real-time assessment of the effectiveness and cost-effectiveness of alternative influenza A/H1N1v vaccination strategies. A transmission dynamic model was fitted to the estimated number of cases in real-time, and used to generate plausible autumn scenarios under different vaccination options. ⋯ The United Kingdom was the first country to have a major epidemic in Europe. In countries where the epidemic is not so far advanced vaccination of children may be cost-effective. Similar, detailed, real-time modelling and economic studies could help to clarify the situation.
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To evaluate the effectiveness of influenza vacation, we conducted analyses at both individual level and health region level. The association between influenza vaccination and hospital admission was examined among 128,677 subjects 12+ years of age who participated in a national survey in 2005. ⋯ Health regions with higher proportions of influenza vaccination had significantly lower proportions of hospitalization. A 10% increase in influenza vaccination less than 1 year ago was associated with a reduction of 11% in the risk of hospitalization over a 12-month time period at the health region level.