Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
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Comparative Study
Comparative dosimetric evaluation of the simultaneous integrated boost with photon intensity modulation in head and neck cancer patients.
The objective of this study is to evaluate, at planning and dosimetric level, the potential benefits of the simultaneous integrated boost (SIB) concept with intensity-modulated radiation therapy (IMRT), using a comparative analysis on physical dose distributions corrected for radiobiological models. The concept of SIB at the end of the treatment has been analysed as an alternative acceleration scheme. ⋯ Feasibility of SIB techniques and in particular of the modified SIB appears to be dosimetrically proven and the results reported here justify the activation of a phase I protocol to verify clinically their impact using IMRT photon-based techniques.