Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
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To compare lung injury among non-small cell lung cancer (NSCLC) patients treated with IMRT or proton therapy as revealed by 18F-FDG post-treatment uptake and to determine factors predictive for clinically symptomatic radiation pneumonitis. ⋯ Despite significantly different dose distributions for IMRT and for protons, the slope of the SUV-dose linear regression line previously shown to be associated with RP did not differ between IMRT and protons. Patients who developed radiation pneumonitis had statistically significantly higher MLD and higher slope regardless of treatment modality.
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To compare ototoxicity rates between medulloblastoma patients treated with protons vs. photons. ⋯ While cochlear doses were lower in the proton group, patients treated with either protons or photons had similar Grade 3 and 4 ototoxicity rates.