European journal of anaesthesiology
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Infusion of ketamine and midazolam can maintain prolonged anaesthesia, but delayed recovery is a limitation. We aimed to develop an approximation regimen for the infusion of ketamine and midazolam to obtain steady-state anaesthesia with acceptable recovery. ⋯ It is concluded that infusion of ketamine and midazolam in the approximation regimen doses can be used to maintain anaesthesia for prolonged abdominal surgery.
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Randomized Controlled Trial Comparative Study Clinical Trial
Minimal flow sevoflurane and isoflurane anaesthesia and impact on renal function.
Compound A generation and accumulation in sevoflurane anaesthesia is dependent on fresh gas flow. We investigated the extent of generation of compound A. ⋯ Compound A concentrations using 0.5 L min-1 fresh gas flow and a heated absorber were higher than previously published values using an inflow of 1 L min-1. Compound A exposure was similar to other clinical studies which did not show changes in renal and hepatic function.
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Randomized Controlled Trial Clinical Trial
Interscalene brachial plexus anaesthesia with small volumes of ropivacaine 0.75%: effects of the injection technique on the onset time of nerve blockade.
We evaluated the effect of the injection technique on the onset time and efficacy of interscalene brachial plexus anaesthesia. ⋯ We conclude that using a multiple injection technique shortened the preparation time and improved the quality of interscalene brachial plexus anaesthesia performed with small volumes of ropivacaine 0.75%.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparative analysis of costs of total intravenous anaesthesia with propofol and remifentanil vs. balanced anaesthesia with isoflurane and fentanyl.
We evaluated the costs and benefits of total intravenous anaesthesia compared with a balanced anaesthesia regimen. ⋯ We conclude that propofol and remifentanil is more cost-effective than isoflurane/fentanyl due to its better recovery profile, reduced total direct costs and higher patient satisfaction.
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of remifentanil and fentanyl in patients undergoing carotid endarterectomy.
We investigated the haemodynamic stability and emergence characteristics of isoflurane/nitrous oxide anaesthesia supplemented with remifentanil or fentanyl in patients undergoing carotid endarterectomy. ⋯ Remifentanil appears to be a comparable opioid to fentanyl when supplementing isoflurane/nitrous oxide anaesthesia for carotid endarterectomy.