Diabetic medicine : a journal of the British Diabetic Association
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The efficacy of the sulphonylurea gliclazide was assessed in 229 non-insulin-dependent diabetics attending U. K. outpatient diabetic clinics. Patients inadequately controlled by diet alone or oral hypoglycaemic agents used reflectance meters to monitor their blood glucose. ⋯ The patients improved in their ability to measure glucose at home and within 2 months a good correlation with laboratory measurements was found. Mean body weight was reduced, particularly in obese and elderly subjects and those treated previously with sulphonylurea drugs. Side effects were mild and only two patients were withdrawn for this reason.