Diabetic medicine : a journal of the British Diabetic Association
-
Randomized Controlled Trial Comparative Study
Amitriptyline vs. pregabalin in painful diabetic neuropathy: a randomized double blind clinical trial.
To compare the efficacy and safety of pregabalin and amitriptyline in alleviating pain associated with diabetic peripheral neuropathy. ⋯ As there are few differences between the two treatments in efficacy, pregabalin 150 mg twice daily might be the alternative choice as it is associated with fewer adverse effects in our population.