Diabetic medicine : a journal of the British Diabetic Association
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Randomized Controlled Trial Multicenter Study
Initiating insulin therapy in elderly patients with Type 2 diabetes: efficacy and safety of lispro mix 25 vs. basal insulin combined with oral glucose-lowering agents.
To compare starter insulins in the elderly subgroup of the DURABLE trial 24-week initiation phase. ⋯ In this elderly subgroup post-hoc analysis, LM25 demonstrated a lower endpoint HbA(1c) and a higher % of patients reaching HbA(1c) target of < 7.0%, but with more weight gain and higher rates of hypoglycaemia compared to glargine.