Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine
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Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent. ⋯ Quantitative estimates of CBF and CBV, obtained with the proposed prebolus DSC-MRI technique, approached those typically obtained by other perfusion modalities. The CBF and CBV estimates showed good repeatability.
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The sophisticated harmonic artifact reduction for phase data (SHARP) method has been proposed for the removal of background field in MRI phase data. It relies on the spherical mean value (SMV) property of harmonic functions, and its accuracy depends on the radius of the sphere used for computing the SMV and truncation threshold needed for deconvolution. The goal of this study was to develop an alternative SMV-based background field removal method with reduced dependences on these parameters. ⋯ The iSMV method is an effective background field removal method with a reduced dependence on method parameters. Magn Reson Med 72:1065-1071, 2014. © 2013 Wiley Periodicals, Inc.
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During MR-guided high-intensity focused ultrasound (HIFU) therapy, ultrasound absorption in the near field represents a safety risk and limits efficient energy deposition at the target. In this study, we investigated the feasibility of using T2 mapping to monitor the temperature change in subcutaneous adipose tissue layers. ⋯ The reversibility and linearity of the T2 -temperature dependence of adipose tissue allows for the monitoring of the temperature in the subcutaneous adipose tissue layers.
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Arterial spin labeling (ASL) perfusion imaging with a segmented three-dimensional (3D) readout is becoming increasing popular, yet conventional motion correction approaches cannot be applied in segmented imaging. The purpose of this study was to demonstrate the integration of 3D pseudocontinuous ASL (PCASL) and PROMO (PROspective MOtion correction) for cerebral blood flow measurements. ⋯ This study demonstrates that PROMO is a successful approach to motion correction for PCASL cerebral blood flow imaging.
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Hyperbaric oxygen therapy has shown efficacies in the treatment of a number of diseases. The goal of this study was to develop a rodent hyperbaric chamber for MRI studies and to investigate the effects of hyperbaric air and hyperbaric oxygen on local magnetic field (B0 ) and MRI relaxation parameters in the rat brain. ⋯ This study establishes the means to perform MRI on rodents under hyperbaric conditions. Hyperbaric air and hyperbaric oxygen have significant effects on B0 and tissue relaxation parameters compared with normobaric air.