Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine
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T2 relaxometry based on multiexponential fitting to a single slice multiecho sequence has been the most common MRI technique for myelin water fraction mapping, where the short T2 is associated with myelin water. However, very long acquisition times and physically unrealistic models for T2 distribution are limitations of this approach. We present a novel framework for myelin imaging which substantially increases the imaging speed and myelin water fraction estimation accuracy. ⋯ The proposed framework can be used for reliable whole brain myelin imaging with a resolution of 2×2×4 mm3 in ≈17 min. Magn Reson Med 76:1301-1313, 2016. © 2015 Wiley Periodicals, Inc.
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To design array-compressed parallel transmit radiofrequency (RF) pulses and compare them to pulses designed with existing transmit array compression strategies. ⋯ Array-compressed pulse design jointly identifies the transmit coil array compression weights and RF pulses that perform best for a specific parallel excitation application. Magn Reson Med 76:1158-1169, 2016. © 2015 Wiley Periodicals, Inc.