Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine
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To accurately correct diffusion-encoding direction-dependent eddy-current-induced geometric distortions in diffusion-weighted echo-planar imaging (DW-EPI) and to minimize the calibration time at 7 Tesla (T). ⋯ The combination of both PSF-based approaches allows distortion-free images, which permit reliable analysis in diffusion tensor imaging applications at 7T.
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To evaluate the performance of relaxation along a fictitious field (RAFF) relaxation time (TRAFF ), diffusion-weighted imaging (DWI)-derived parameters, and T2 relaxation time values for prostate cancer (PCa) detection and characterization. ⋯ In a quantitative region of interest-based analysis, RAFF outperformed DWI ("low" and "high" b values) and T2 mapping in the characterization of PCa.
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Macromolecular proton fraction (MPF) mapping is a quantitative MRI method that reconstructs parametric maps of a relative amount of macromolecular protons causing the magnetization transfer (MT) effect and provides a biomarker of myelination in neural tissues. This study aimed to develop a high-resolution whole brain MPF mapping technique using a minimal number of source images for scan time reduction. ⋯ The proposed synthetic reference method improves resolution of MPF mapping and combines accurate MPF measurements with unique neuroanatomical contrast features.