Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine
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To investigate gradient-echo phase errors caused by intracranial hemorrhage (ICH) of low signal magnitude, and propose methods to reduce artifacts from phase errors in quantitative susceptibility mapping (QSM) of ICH. ⋯ The proposed methods of mask-inversion as well as ICH isolation and superposition can substantially reduce artifacts in QSM of ICH. Magn Reson Med 76:781-791, 2016. © 2015 Wiley Periodicals, Inc.
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The echo time (TE) averaged spectrum is the one-dimensional (1D) cross-section of the J-resolved spectrum at J = 0. In multiecho TE-averaged spectroscopy, glutamate (Glu) is differentiated from glutamine (Gln) at 3 Tesla (T). This method, however, almost entirely suppresses Gln resonance lines around 2.35 ppm, leaving Gln undetermined. This study presents a novel method for quantifying both Glu and Gln using multi-echo spectral data. ⋯ Gln resonances can be clearly separated from Glu and N-acetyl-aspartate around 2.35 ppm using J-modulated spectroscopy. This method can be used to quantitatively measure Glu and Gln simultaneously at 3T. Magn Reson Med 76:725-732, 2016. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.
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To evaluate the use of variable flip angle refocusing pulse trains in single-shot three-dimensional gradient and spin-echo (3D-GRASE) to reduce blurring and increase the spatial coverage for high spatial resolution T2 -weighted functional MRI at 7 Tesla. ⋯ Variable flip angle refocusing schemes increase usability of 3D-GRASE for high-resolution functional MRI by reducing blurring and allowing increased spatial coverage. Magn Reson Med 76:897-904, 2016. © 2015 Wiley Periodicals, Inc.
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To reduce saturation effects in the arterial input function (AIF) estimation of quantitative myocardial first-pass saturation recovery perfusion imaging by employing a model-based reconstruction. ⋯ The application of model-based reconstruction algorithms in quantitative myocardial perfusion imaging promises a significant improvement of the AIF determination. In addition to greatly reducing saturation effects that occur even for the prebolus methods, only a single bolus has to be applied. Magn Reson Med 76:880-887, 2016. © 2015 Wiley Periodicals, Inc.