Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine
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The purpose of this work is to derive and demonstrate constrained-phase dual-echo Dixon imaging within a maximum likelihood framework solved with a regularized graph-cuts-guided optimization. ⋯ Constrained-phase dual-echo Dixon imaging solved with a regularized graph-cuts-guided optimization has been derived and demonstrated to successfully separate water and fat images in the presence of large magnetic field inhomogeneities. Magn Reson Med 78:2203-2215, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
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Comparative Study
A comparative simulation study of bayesian fitting approaches to intravoxel incoherent motion modeling in diffusion-weighted MRI.
To assess the performance of various least squares and Bayesian modeling approaches to parameter estimation in intravoxel incoherent motion (IVIM) modeling of diffusion-weighted MRI data. ⋯ Bayesian modeling is capable of producing more visually pleasing IVIM parameter maps than least squares approaches, but their potential to mask certain tissue features demands caution during implementation. Magn Reson Med 78:2373-2387, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
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In order to benefit from the increased spectral bandwidth at ultrahigh field (UHF), the use of parallel transmission (pTx) to mitigate flip-angle inhomogeneity in chemical exchange saturation transfer (CEST) imaging is investigated. ⋯ A pTx-based pulsed CEST presaturation scheme is proposed and validated by simulations and 7T in vivo imaging. Magn Reson Med 78:2216-2225, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
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To develop a radial, double-echo steady-state (DESS) sequence with ultra-short echo-time (UTE) capabilities for T2 measurement of short-T2 tissues along with simultaneous rapid, signal-to-noise ratio (SNR)-efficient, and high-isotropic-resolution morphological knee imaging. ⋯ The T2 measurements of short-T2 tissues and high-resolution morphological imaging provided by UTEDESS makes it promising for studying the whole knee, both in routine clinical examinations and longitudinal studies. Magn Reson Med 78:2136-2148, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
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To simultaneously measure concentration and T1 and T2 values of metabolites in the human brain in a single scan session. ⋯ The proposed technique allows multiparametric characterization of brain metabolites in a single scan session, making it possible to measure both levels and intracellular microenvironments of brain chemicals in clinical MR spectroscopy studies. Magn Reson Med 78:2072-2081, 2017. © 2017 International Society for Magnetic Resonance in Medicine.