Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine
-
Conventional T1 mapping using three-dimensional (3D) radiofrequency (RF) spoiled gradient echo (SPGR) imaging with short repetition times (TR) is adversely affected by incomplete spoiling (i.e. residual T2 dependency). In this work, an optimized interleaved 2D multislice SPGR sequence scheme and an adapted postprocessing procedure are evaluated for highly T2 -insensitive T1 quantification of human brain tissues. ⋯ The derived 2D multislice SPGR protocol offers efficient, highly reproducible, and in particular T2 -insensitive T1 quantification of human brain tissues. Magn Reson Med 77:1606-1611, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
-
Simultaneous multislice (SMS) has been proved to be powerful for accelerating single-shot echo-planar imaging (ssh-EPI) based diffusion-weighted imaging (DWI), but there are some obstacles for applying SMS to interleaved echo-planar imaging (iEPI) DWI. The primary challenge is to effectively combine slice unfolding for SMS and intershot phase correction for multishot DWI. In this study, a novel acquisition and reconstruction method for SMS-accelerated high-resolution iEPI DWI is proposed. ⋯ The proposed acquisition and reconstruction is an effective method for accelerating multishot high-resolution DWI, which may be valuable for both neuroscience research and clinical diagnosis. Magn Reson Med 77:1593-1605, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
-
To develop and validate a dual-contrast image subtraction (DCIS) strategy for eliminating the flow artifacts in black-blood carotid MRI. ⋯ DCIS is demonstrated to be an effective strategy for sufficiently removing the residual flow signal from black-blood carotid MRI. Magn Reson Med 77:1612-1618, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
-
Susceptibility-based blood oxygenation measurements in small vessels of the brain derive from gradient echo (GRE) phase and can provide localized assessment of brain function and pathology. However, when vessel diameter becomes smaller than the acquisition voxel size, partial volume effects compromise these measurements. The purpose of this study was to develop a technique to improve the reliability of vessel oxygenation estimates in the presence of partial volume effects. ⋯ JUMP exploits both magnitude and phase data in GRE imaging to mitigate partial volume effects in estimation of vessel oxygenation. Magn Reson Med 77:1713-1727, 2017. © 2016 International Society for Magnetic Resonance in Medicine.