Current opinion in gastroenterology
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Graft-versus-host disease (GVHD) is a common, potentially life-threatening complication of allogenic hematopoietic stem cell transplantation. Gastrointestinal GVHD frequently involves the colon and complicates management of these seriously ill patients. This review updates the diagnosis and management of colonic GVHD. ⋯ Although colonic GVHD is readily diagnosed, advances in management await greater understanding of pathogenesis and more specifically targeted therapies.