Current opinion in gastroenterology
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Curr. Opin. Gastroenterol. · Jan 2017
ReviewProgress with treating the microbial dysbiosis associated with irritable bowel syndrome.
Microbial dysbiosis is receiving increasing attention as possibly being important in the pathophysiology of irritable bowel syndrome. This review will summarize the most recent literature addressing attempts to explore and target the microbiome in patients with irritable bowel syndrome. ⋯ The manipulation of the microbial dysbiosis is gaining momentum. Further research, however, is required in order to identify the most appropriate treatment option for each individual patient.
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Curr. Opin. Gastroenterol. · Jan 2017
ReviewFecal microbiota transplantation for gastrointestinal disorders.
The importance of the gut microbiome in human health is being increasingly recognized. The purpose of this review is to examine the existing literature pertaining to alterations in the gut microbiome and the utility of microbiome restoration therapies in gastrointestinal disorders. ⋯ Alterations in the gut microbiome are associated with several disorders, and microbiome restoration based therapies such as fecal microbiota transplantation may be an adjunct to conventional treatments but more investigation is needed.