Annals of Saudi medicine
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Annals of Saudi medicine · May 2005
Comparative Study Clinical Trial Controlled Clinical TrialQuantification of proteinuria with urinary protein to osmolality ratios in children with and without renal insufficiency.
Spot urine is recommended as an accurate method to determine proteinuria in children and adults. However, urinary excretion of creatinine may vary in newborns and spot urine may be influenced by the hydration-dehydration condition of patients. The study was done to assess the validity of the urine protein to osmolality ratio versus the urine protein to creatinine ratio in health and disease conditions. ⋯ Both the Uprot/Uosm and Up/Ucr ratios from random urine specimens are good predictors of 24-hour urinary total protein excretion in children with and without renal insufficiency.