Annals of Saudi medicine
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Annals of Saudi medicine · Nov 2016
Randomized Controlled Trial Multicenter StudyRe-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial.
Clinicians routinely administer stress ulcer prophylaxis to mechanically ventilated patients in the intensive care unit (ICU), most commonly prescribing proton pump inhibitors (PPIs). However, the incidence of gastrointestinal (GI) bleeding from stress ulceration is low and recent observational studies suggest these agents may increase infections. Therefore, a large randomized clinical trial (RCT) is needed to inform modern practice. The aim of this multicenter pilot trial is to determine the feasibility of performing a large RCT to investigate the efficacy and safety of withholding intravenous pantoprazole. ⋯ This study has been approved by Health Canada, and research ethics board (REB) at each of the participating centers.
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Annals of Saudi medicine · Nov 2016
Clinical TrialGlycemic indices, glycemic load and glycemic response for seventeen varieties of dates grown in Saudi Arabia.
Dates are consumed worldwide, and are an important fruit for many individuals in Saudi Arabia. Currently, limited information is available on the glycemic indices of different date varieties. ⋯ We used dates at the Tamer stage, which may not be translatable to all types of dates.
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Annals of Saudi medicine · Nov 2016
Leptin and calorie intake among different nicotine dependent groups.
Exposure to nicotine via tobacco smoking may influence leptin release and decrease food intake among smokers. However, the effect of nicotine exposure on leptin and food intake among different nicotine dependent groups is unclear. ⋯ Purposive sampling for subject recruitment and inaccurate information in the self-administered questionnaire.