Annals of Saudi medicine
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Annals of Saudi medicine · Jan 2021
Seropositivity of syphilis among individuals screened in a tertiary hospital in the Eastern Province of Saudi Arabia.
Sexually transmitted infections are a serious public health problem. Syphilis, a multistage, curable chronic disease caused by the spirochete Treponema pallidum, remains a major health problem worldwide. The disease re-emerged in the era of HIV in many countries despite the accessibility of curative therapy and continuing public health efforts to eliminate it. ⋯ None.
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Annals of Saudi medicine · Jan 2021
Gender differences in completed suicidal hangings from 2013 to 2018 in Muğla, Turkey.
Hanging is the most preferred among suicide methods. Although methods vary based on age groups and social and cultural conditions, many studies have reported it as the most common suicide method in Turkey. ⋯ None.
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Annals of Saudi medicine · Jan 2021
The value of repeating fine-needle aspiration for thyroid nodules.
Fine-needle aspiration (FNA) is an invaluable technique used in the evaluation of thyroid nodules. ⋯ None.
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Annals of Saudi medicine · Jan 2021
Prevalence of methylenetetrahydrofolate reductase gene polymorphisms (C677T, and A1298C) among Saudi children receiving dental treatment.
Methylenetetrahydrofolate reductase, the encoded by the MTHFR gene, plays a crucial role in converting the amino acid homocysteine to methionine. Two polymorphisms of the MTHFR gene, C677T and A1298C, reportedly reduce enzyme activity, resulting in hyperhomocysteinemia. Patients with C677T and A1298C polymorphisms may be at higher risk for developing abnormal hyperhomocysteinemia, which has been linked to catastrophic neurological including fatal outcomes. ⋯ None.
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Annals of Saudi medicine · Jan 2021
Case ReportsVon Willebrand disease type 2B with a novel mutation in the VWF gene.
We report a 38-year-old woman who presented with a subdural hematoma after minor facial trauma in a stressful situation. The laboratory data showed a subnormal platelet count (166×109/L), VWF:RCo activity was 45% and VWF:Ag was 53% with a VWF:RCo/VWF Ag ratio of 0.79. Hemostasis results and gene analysis revealed von Willebrand disease (VWD) type 2B with normal multimers and a novel mutation c.4136 G>T (R1379L), which appears to be a novel mutation of VWD type 2B that is mainly diagnosed with hypersensitivity to ristocetin and an hyperfixation of platelet Willebrand to a recombinant Gp1b. SIMILAR CASES PUBLISHED: None.