Anaesthesia and intensive care
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Anaesth Intensive Care · Aug 2003
Randomized Controlled Trial Clinical TrialCryoprecipitate for the correction of coagulopathy associated with liver disease.
In patients with liver disease at risk of pulmonary oedema, cryoprecipitate (small volume) might be a viable alternative to fresh frozen plasma (FFP, large volume) in the correction of coagulopathy. However, the efficacy of cryoprecipitate in these patients has not been tested. We evaluated the role of cryoprecipitate in the correction of the coagulopathy of liver disease. ⋯ Cryoprecipitate improves the coagulopathy of liver disease. Four units of FFP are more efficacious than five units of cryoprecipitate. Cryoprecipitate may have a role in correction of the coagulopathy associated with liver disease where concerns about pulmonary oedema exist.
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Anaesth Intensive Care · Aug 2003
Clinical Trial Controlled Clinical TrialSimulated epidural test doses using adrenaline and adrenaline/clonidine in sevoflurane-anaesthetized children.
A pilot study was conducted using a simulated epidural test dose to ascertain the effects adrenaline, adrenaline/clonidine mixture, and clonidine alone on the accepted criteria for determining the occurrence of an epidural intravascular injection. Seventy-five ASA 1 or 2 children aged from six months to twelve years were sequentially allocated to one of three groups: group A: adrenaline 0.5 microgram/kg, group AC: adrenaline 0.5 microgram/kg and clonidine 0.3 microgram/kg, and group C: clonidine 0.3 microgram/kg. Effects on heart rate, T-wave amplitude and systolic blood pressure were determined after induction of anaesthesia and stabilization using sevoflurane in nitrous oxide and oxygen. ⋯ There were no significant differences between groups A and AC for any parameter. Negative predictive value estimates for the current criteria for intravascular injection were low. Clonidine 0.3 microgram/kg produced no effects on the study variables.
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Anaesth Intensive Care · Aug 2003
Case ReportsAirway rescue with the ProSeal laryngeal mask airway in the intensive care unit.
We report the successful use of the ProSeal laryngeal mask airway for airway rescue in a 41-year-old septic patient who could be neither intubated nor facemask ventilated. In principle, the ProSeal laryngeal mask airway offers advantages over the Classic LMA in this situation.