The Clinical journal of pain
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The International Association for the Study of Pain defines allodynia as pain due to a stimulus that does not normally provoke pain and hyperalgesia as an increased response to a stimulus, which is normally painful. However, does "normally painful" mean "any stimulation of nociceptors" or "the subjective pain response?" We argue that "normally painful" should not mean "any stimulation of nociceptors," as Von Frey monofilaments may evoke a pricking sensation--which implies the involvement of nociceptors--without necessarily leading to a subjective pain perception. In this paper, we propose that the diagnosis of either allodynia or hyperalgesia should be based on the patient's report, that is, painful versus not painful, rather than on the (sub) type of afferent fiber involved.
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Deep cross-friction pressure with a finger or an elbow in the proximal gluteal region causes a sciaticlike pain along the side of the thigh and the leg as a clinical presence of referred pain (RP) in patients with nonspecific low back pain (LBP). This study investigated the reliability and discriminative ability of experimentally provoked RP as a result of deep cross-friction with the aid of a Fischer algometer. The new clinical examination method measures the provoked RP threshold resulting in an outcome, expressed in kg/cm2. ⋯ This clinical study support the reliability and discriminative ability of a new method of experimentally provoked RP, using deep cross-friction pressure with the aid of a Fischer algometer in patients with LBP. The experimentally "provoked referred pain threshold" (PPT-RP) values lower than 6 kg/cm correspond clinically with the presence of a referred muscle pain area in the thigh and/or the leg. Further studies of a similar kind are nevertheless needed to confirm those conclusions and to assess the responsiveness of the provoked RP measurements in different treatment follow-up periods.
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The Depression, Anxiety, and Positive Outlook Scale (DAPOS) was designed to measure mood in pain populations without contamination from somatic items. ⋯ Responsiveness of the DAPOS should be reassessed in treatment targeting mood change explicitly. The DAPOS scales show acceptable clinimetric and psychometric properties, and add a measurement of positive outlook to create a more balanced indication of mood in pain patients.
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Correlates of pain-rating concordance for adolescents with sickle cell disease and their caregivers.
As sickle cell pain in children and adolescents with sickle cell disease (SCD) is managed primarily at home, understanding convergence of caregiver and youth pain reports may contribute to improvements in home pain management. The goal of this study was to examine concordance in pain ratings for a sample of 53 adolescents with SCD and their caregivers and to assess sociodemographic and psychosocial factors associated with concordance. ⋯ Efforts to improve home management of pain in SCD should incorporate programming designed to increase parent-child communication about pain and pain interference, confidence in disease management abilities, and improved knowledge of SCD and its care, particularly for families of older adolescents.
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There is no consensus among experts regarding the etiology or management of patellofemoral pain syndrome (PFPS). Observations indicating dysfunction of the peripheral nervous system around the patellae have been reported. To what extent these sensory abnormalities cause pain has so far not been investigated. The aim of this study was to assess whether a subgroup of patients with unilateral PFPS have neuropathic pain related to the painful knee. ⋯ This study hypothesizes that the observed sensory aberrations may cause neuropathic pain in patients with PFPS. There is no validated method for subgrouping patients with possible neuropathic pain and in this study considerable heterogeneity and overlap regarding signs and symptoms of neuropathic pain made subgrouping even more difficult. A mechanism-based understanding of the pain is, however, essential for the selection of adequate treatment strategies in painful musculoskeletal disorders.