The Clinical journal of pain
-
Randomized Controlled Trial
Pain coping but not readiness to change is associated with pretreatment pain-related functioning.
The purpose of the present study was to determine if readiness to use adaptive and avoid maladaptive pain-coping skills before initiation of psychosocial treatment for chronic pain was related to reports of present coping, and whether those variables, together or separately, explained variance in pain, pain interference, and symptoms of depression. ⋯ Overall, the results indicate that adaptive coping is associated with better pain-related functioning and maladaptive coping is associated with poorer functioning, whereas readiness appears to not play a significant role in patient functioning before psychosocial pain treatment. The findings support the discriminant validity of the coping and readiness measures and inform treatment conceptualization.
-
To provide a current overview of the diagnostic work-up and management of painful diabetic polyneuropathy (PDPN). ⋯ As efficacy and tolerability of current therapy for PDPN are not ideal, the need for a better approach in management further exists. Novel compounds should be developed for the treatment of PDPN.
-
Randomized Controlled Trial
The pain quality response profile of pregabalin in the treatment of neuropathic pain.
To identify and describe the response profile of pregabalin on the qualities of pain associated with peripheral neuropathy. ⋯ Pregabalin had a greater effect on PQAS-assessed paroxysmal pain than on surface or deep pain in patients with peripheral neuropathy. The findings corroborate previous research demonstrating differential effects of analgesic drugs across pain qualities, further emphasizing the need to assess individual pain qualities in addition to overall pain intensity.
-
To identify predictive factors for the occurrence of postherpetic neuralgia (PHN). ⋯ Our study indicates that advanced age and deep pain at the initial visit are significant predictors for PHN. Our results are considered likely to contribute to the establishment of evidence-based medicine in the optimal treatment of PHN.
-
To assess pain burden in neonates during their hospitalization in China and thus provide evidence for the necessity of neonatal pain management. ⋯ Neonates, particularly preterm neonates, were exposed to numerous invasive painful procedures without appropriate analgesia in hospitals in China. The potential long-term impacts of poorly treated pain in neonates call for a change in pediatric practice in China and in countries with similar practices.