The Clinical journal of pain
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Randomized Controlled Trial
Effects of Adding Oxycodone to Ropivacaine on Labor Analgesia: A Randomized Controlled Trial.
It's known that the addition of opiates to LA improves epidural analgesia in labour. This trial should have compared oxycodone to fentanyl.
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Randomized Controlled Trial
Illusion-enhanced Virtual Reality Exercise for Neck Pain: A Replicated Single Case Series.
Body illusions have shown promise in treating some chronic pain conditions. We hypothesized that neck exercises performed in virtual reality (VR) with visual feedback of rotation amplified would reduce persistent neck pain. ⋯ Our hypothesis, that neck exercises performed in VR with visual feedback of rotation amplified, would reduce persistent neck pain was not supported. Possible explanations and future directions are discussed.
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Randomized Controlled Trial
The Benefit of Dexmedetomidine on Postoperative Cognitive Function is Unrelated to the Modulation on Peripheral Inflammation: A Single Center, Prospective, Randomized Study.
Dexmedetomidine potentially confers an advantage to reduce the incidence of postoperative delirium (POD) in surgical patients. Anti-inflammation is important effect of this sedative drug. In this study, we aimed to investigate whether the effect of dexmedetomidine on the postoperative cognitive function is via inhibiting peripheral inflammation. ⋯ Intraoperative sedation with dexmedetomidine conferred better postoperative neurocognitive function for elderly patients who received total knee arthroplasty. This effect was unrelated to the modulation of dexmedetomidine on peripheral inflammation.
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The purpose of the current study was to investigate the influence of sleep on the relationship between pain and health care use (HCU) in youth with sickle cell disease (SCD). It was hypothesized that poor sleep would be related to higher HCU and would strengthen the relationship between high pain frequency and more HCU among youth with SCD. ⋯ Findings suggest that good sleep may serve as a protective factor for better matching pain to HCU. Results should be interpreted in the context of study limitations. Research is needed to investigate possible mechanisms linking sleep duration to HCU in response to pain and to ascertain if sleep patterns influence the relationship between pain and other functional outcomes in youth with SCD. Clinically, these findings support the need to acknowledge and address the role that sleep plays in responding to SCD pain in pediatric populations.