The Clinical journal of pain
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Phantom limb pain is difficult to treat as existing therapies have limited effectiveness and what works for one person may not work for another. This makes the fact that research is ongoing and advancing even more important to many people who have this problem. We are reporting a case of intractable phantom limb pain whose pain did not respond to usual line of treatment and only high dose of morphine made the patient totally pain free.
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The aim of this study is to investigate whether quantitative sensory testing with Von Frey monofilaments (VFMs) can be used for the quantification of allodynia in patients with chronic neuropathic pain, and how the pain threshold of affected skin differs from healthy skin. ⋯ We showed that although etiology and pathophysiology of allodynia vary individually, with VFMs the clinical symptom allodynia can be quantified in a simple and practical fashion in almost all patients.
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This study explores the fear-avoidance model in a sample of women with neck-shoulder pain related to computer work who were still functioning at the workplace. Exploring this model in this population could produce starting points for new treatment approaches in occupational health. ⋯ In line with the fear-avoidance model, the current results addressed the importance of pain-related fear in people with neck-shoulder pain disability related to computer work. Interestingly, and not in accordance with the fear-avoidance model, fear-avoidance beliefs directly influence disability levels in the current sample; regardless of lower levels of performance that is, physical impairment.
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Randomized Controlled Trial
A randomized, placebo-controlled study of fentanyl buccal tablet for breakthrough pain in opioid-treated patients with cancer.
Cancer-related breakthrough pain (BTP) is typically managed with a short-acting oral opioid, taken as needed during a fixed-schedule opioid regimen. The conventional approach may not provide the onset of analgesia required for BTP for many patients, because the onset of analgesia with short-acting opioids lags behind the time course of the majority of episodes of BTP. The fentanyl buccal tablet (FBT) employs a novel delivery system that enhances the rate and extent of absorption of fentanyl through the buccal mucosa. This double-blind, randomized, placebo-controlled study evaluated the efficacy, safety, and tolerability of FBT in opioid-treated patients with cancer-related BTP. ⋯ FBT is efficacious and safe in the treatment of cancer-related BTP.
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Multicenter Study Clinical Trial
The validity and reliability of the graphic rating scale and verbal rating scale for measuring pain across cultures: a study in Egyptian and Dutch women with rheumatoid arthritis.
To compare the validity and reliability of a graphic rating scale (GRS) and a verbal rating scale (VRS) for measuring pain intensity in young female Egyptian and Dutch patients with rheumatoid arthritis (RA). ⋯ The study confirmed that the GRS and VRS were reliable and valid in the total study cohort. Within the individual countries, the GRS seemed to perform better than the VRS.