The Clinical journal of pain
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Comparative Study
Myofascial disorders in the trochlear region in unilateral migraine: a possible initiating or perpetuating factor.
Some patients with trochlear disorders have been found to suffer from concurrent migraine. However, a trochlear examination is not systematically done in patients with migraine. Moreover, a search for myofascial trigger points in the superior oblique muscle has never been reported in these patients. ⋯ Patients with unilateral migraine commonly perceive referred pain from the trochlear area that probably comes from the myofascial trigger points. Myofascial disorders in the trochlear region might contribute to the perpetuation of concomitant migraine.
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Randomized Controlled Trial Comparative Study Clinical Trial
Topiramate in treatment of patients with chronic low back pain: a randomized, double-blind, placebo-controlled study.
Chronic low back pain (CLBP) is a widespread ailment. The aim of this study was to assess the efficacy of topiramate in the treatment of CLBP and the changes in anger status and processing, body weight, subjective pain-related disability and health-related quality of life during the course of treatment. ⋯ Topiramate seems to be a relatively safe and effective agent in the treatment of CLBP. Significantly positive changes in pain sensitivity, anger status and processing, subjective disability, health-related quality of life, and loss of weight were observed.
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Comparative Study
Predictors of incident chronic widespread pain among veterans following the first Gulf War.
We sought to determine the predictors of incident chronic widespread pain (CWP), specifically, the effect of preexisting symptoms, stress, and psychosocial factors in the subsequent development of CWP among veterans from the first Gulf War (GW). ⋯ Among the GW veterans evaluated longitudinally in this study, family history, predeployment symptoms, and the level of perceived stress during the GW were associated with subsequent development of CWP.
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Comparative Study
Effect of disease-related pain on the health-related quality of life of children and adolescents with cystic fibrosis.
The authors' objective was to describe the effect of recurrent pain symptoms on the health-related quality of life (HRQOL) of children and adolescents with cystic fibrosis (CF). Frequent pain, independent of disease severity, was hypothesized to be associated with broad decrements in physical, psychological, and social functioning. ⋯ Children with frequent CF-related pain experienced broad decrements in their HRQOL. These findings are similar to those found in other populations of children experiencing disease-related pain, suggesting a pervasive impact of pain on overall health and well-being. Future research is needed to evaluate treatments to reduce pain symptoms and improve HRQOL in children with cystic fibrosis.
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Comparative Study
Adolescent-parent relationships in the context of adolescent chronic pain conditions.
This study explored adolescent-parent relationships in families of adolescents with chronic pain. ⋯ The findings suggest important directions for future research to advance our understanding of the role of adolescent-parent relationships in the pain-disability cycle.