Pediatric emergency care
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Pediatric emergency care · Jan 2008
Randomized Controlled TrialPilot study of oral montelukast added to standard therapy for acute asthma exacerbations in children aged 6 to 14 years.
We hypothesized that children with moderate acute asthma exacerbations receiving oral montelukast with standard therapy will have at least 12% greater forced expiratory volume in 1 second (FEV1) improvement in 3 hours than those receiving standard therapy alone. ⋯ Based on these results, for children aged 6 to 14 years with moderate acute asthma exacerbations, oral montelukast (5 mg) added to standard therapy as in this design is unlikely to result in additional FEV1 improvements in 3 hours.