Critical care clinics
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Critical care clinics · Oct 1988
ReviewTherapeutic strategies for acute hypoxemic respiratory failure.
Acute hypoxemic respiratory failure is a pulmonary capillary leak state that occurs in many different clinical settings. The resultant edema causes refractory hypoxemia due to intrapulmonary shunting and loss of lung compliance. Mechanical ventilation with PEEP and high concentrations of supplemental oxygen are frequently necessary for patient survival, but these therapies may themselves contribute to further lung damage. ⋯ The use of these combined modalities for pediatric patient care has been discussed. Finally, other approaches to treatment currently being investigated in animal models of AHRF have been presented. As these and other new treatment methods are explored, hopefully it will be possible to decrease the unacceptably high mortality rate still encountered in AHRF.
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Critical care clinics · Oct 1988
ReviewBronchopulmonary dysplasia in the pediatric intensive care unit.
Bronchopulmonary dysplasia (BPD) is an important cause of chronic respiratory disease in infants and children. Infants with BPD are frequently readmitted to the hospital during the first 2 years of life usually because of infectious exacerbations of their chronic lung disease. This article is a review of the multisystem pathology of BPD and therapeutic approaches to the management of these infants in the PICU.