Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
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Otolaryngol Head Neck Surg · Jul 2004
Comparative StudyOtotoxic protection of sodium thiosulfate: daily vs constant infusion.
Compare the effect of a daily dose of sodium thiosulfate (STS) to continuous infusion of STS on Hartley albino guinea pig (HAGP) on cisplatin (CP)-induced sensorineural hearing loss. Study design Prospective randomized pilot study comparing a single daily dose of STS to a constant controlled infusion of STS given the middle ear space (MES) with an ototoxic regimen of CP. The hearing thresholds will be obtained by auditory brainstem response (ABR) 1 week before and after treatment. Treatment effects on responses at 2, 8, and 16 kHz signals will be investigated by an analysis of variance with one between subjects' condition and two within subjects' conditions. ⋯ Any targeted protection, whether by continuous infusion or daily dose, is better than no protection against the sensorineural hearing loss of CP.
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Otolaryngol Head Neck Surg · Jul 2004
Adenotonsillectomy for obstructive sleep apnea in obese children.
To study changes in sleep behavior and quality of life in obese children after adenotonsillectomy for obstructive sleep apnea. Study design and setting Prospective study at the University of New Mexico Children's Hospital. ⋯ Obese children with OSA who undergo adenotonsillectomy show a marked improvement in RDI and in quality of life with no change in BMI. However, in the majority of children, OSA does not resolve.
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Otolaryngol Head Neck Surg · Jul 2004
Comparative StudyRemoval of fish bones in the oropharynx and hypopharynx under video laryngeal telescopic guidance.
The study goal was to present the technique and results of removal of fish bones in the oropharynx and hypopharynx under video laryngeal telescopic guidance. Study design and set From January 2001 to December 2002, a total of 27 patients with fish bones lodged in the oropharynx and hypopharynx were studied at the ENT Department of Taipei Medical University Hospital. ⋯ Removal of the fish bones from difficult areas in oropharynx and hypopharynx with this technique can reduce the use of direct laryngoscope under general anesthesia.