Pediatric neurology
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Acute cerebellitis is a rare inflammatory syndrome in children, with either infectious or autoimmune etiologies. ⋯ Our report demonstrates that group A streptococcal can lead to acute cerebellitis.
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Pediatric neurology · Nov 2013
Thrombolysis for children with acute ischemic stroke: a perspective from the kids' inpatient database.
Thrombolysis for acute ischemic stroke (AIS) in children is yet to be proven efficacious, and there is limited information about its safety in large pediatric samples. Here we evaluate the safety outcomes associated with thrombolysis in children as well as the trend of hospital utilization over the past decade in the United States. ⋯ Thrombolysis for acute ischemic stroke is infrequently used in children. There is a trend toward higher risks of intracerebral hemorrhage and hospital mortality, although these risks are as low as those reported in adult population. The hospitals' utilization of thrombolysis in children has increased during the study period.
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Pediatric neurology · Nov 2013
Role of intravenous levetiracetam for acute seizure management in preterm neonates.
Neonatal seizures are common in the first month of life and may impair neurodevelopmental outcome. Current antiepileptic drugs used in the treatment of neonatal seizures have limited efficacy and undesirable side effects. Intravenous levetiracetam is increasingly being used in the neonatal period to treat seizures. Presently, insufficient data about the efficacy and safety of intravenous levetiracetam in preterm neonates exist. ⋯ Intravenous levetiracetam appears to be efficacious for seizure management in preterm neonates.
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Pediatric neurology · Nov 2013
Posterior reversible encephalopathy syndrome: incidence and associated factors in a pediatric critical care population.
Posterior reversible encephalopathy syndrome may occur frequently and be underrecognized in children and young adults admitted to a pediatric critical care unit. ⋯ Our case cohort includes an estimation of incidence of posterior reversible encephalopathy syndrome in children and young adults with 1-year follow-up and anemia as a potential previously unreported risk factor.