Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Nov 1994
Infrared pupillometry in the assessment of autonomic function.
In order to study normal dynamic pupillary function and to determine reference limits for various pupillary variables, 81 healthy subjects aged between 32 and 60 years were examined using a portable infrared pupillometer. Additionally, 36 patients with type I diabetes mellitus were studied. In healthy subjects, sex had no, or only marginal, effect on the responses. ⋯ The smaller the RRA was, the slower the velocities and the shorter the t75% were. Using these reference limits, 25% of the diabetic patients without cardiac autonomic neuropathy and 50% with definite cardiac autonomic neuropathy had abnormalities in at least one out of four pupillary variables. It is concluded that infrared pupillometry may be a useful additional method for the assessment of autonomic function.