Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Dec 2012
Randomized Controlled Trial Comparative StudyMetformin compared with insulin in the management of gestational diabetes mellitus: a randomized clinical trial.
To evaluate the effect of metformin and insulin in glycemic control and compare pregnancy outcome in women with gestational diabetes mellitus (GDM). ⋯ Metformin is an effective and safe alternative treatment to insulin for women with GDM. This study does not show significant risk of maternal or neonatal adverse outcome with the use of metformin.
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Diabetes Res. Clin. Pract. · Dec 2012
Clinical evaluation of a novel test strip technology for blood glucose monitoring: accuracy at hypoglycaemic glucose levels.
To evaluate OneTouch® Verio™ test strip performance at hypoglycaemic blood glucose (BG) levels (<3.9 mmol/L [<70 mg/dL]) at seven clinical studies. ⋯ In this analysis of data from seven independent studies, OneTouch Verio test strips provide highly accurate results at hypoglycaemic BG levels.
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Diabetes Res. Clin. Pract. · Dec 2012
C-peptide response to glucagon challenge is correlated with improvement of early insulin secretion by liraglutide treatment.
The amelioration of glucose tolerance by liraglutide was associated with a significant improvement of early insulin-response during OGTT. The serum C-peptide response to glucagon challenge strongly correlated with the improvement of the early insulin-response. The C-peptide response to glucagon challenge would be useful to predict therapeutic response to liraglutide.